Skin care · Topical skin protectant / antipruritic

Calamine lotion

Calamine lotion is a gentle topical liquid that soothes itch, irritation, and mild sunburn on the skin.

OTCPaediatric useSenior precaution
Calamine LotionCaladrylNixoderm
Overview & typical uses

Calamine lotion is a gentle topical liquid that soothes itch, irritation, and mild sunburn on the skin.

Primary uses

  • Relief of itch from insect bites
  • Mild rashes, prickly heat
  • Sunburn or minor skin irritation
How it works

Zinc oxide and iron oxide gently cool, soothe, and dry the skin surface to reduce itching and irritation.

Available forms & strengths
  • Topical lotion (Topical)
General precautions & contraindications

Do not use if

  • Do not apply to broken or infected skin

Pregnancy

Generally considered safe. Not systemically absorbed; safe in pregnancy.

Breastfeeding

Generally considered safe. Safe during breastfeeding.

Paediatric use

Safe from infancy on intact skin.

Older adults

Safe and useful for itchy skin.

Common side effects
  • Rare mild skin irritation
Food & alcohol precautions

No notable food interactions recorded.

Storage, missed dose & overdose

Storage

Store at room temperature. Shake well before use.

If a dose is missed

Apply as needed for comfort.

Overdose

Overdose is not clinically relevant with topical use.

Frequently asked questions
Can I use calamine on chickenpox itch?

Yes — it is commonly used to soothe chickenpox itch on unbroken skin.

Medical references
  • WHO Model Formulary — Topical skin careWorld Health Organization

Content last reviewed: 2025-01-01

Medical disclaimer

This information is for educational purposes only and should not replace professional medical advice. Please consult a licensed pharmacist or clinician for advice tailored to your personal circumstances.